Program and book of abstracts 1st conference

1 st Conference of European Academy for Molecular Hydrogen Research in Biomedicine “Hydrogen for Biomedicine“

Russell Grace

Grace Russell graduated fromUniversity of theWest of England (UWE) with anMSci in Biomedical Sciences, 2020, with distinction. Grace is continuing her research into the effects of molecular hydrogen and oxy-hydrogen gases as a UWE doctoral candidate. Her wider research interests include cellular evolution and natural, traditional, and sustainable medications throughout history. Although Grace is at the beginning of her academic journey, she has numerous publications in respected peer-reviewed journals and has authored a book on the topic of molecular hydrogen. Grace has recently been appointed as a post graduate representative on the AthenaSWAN equalities committee at UWE and is passionate about inclusivity and intersectional representation in Science, Technology, Engineering, and Mathematics (STEM). Grace is certified by the Molecular Hydrogen Institute (USA) as an H2 advisor and has completed a post graduate academic course in professional scientific practice. THE INFLUENCE OF OXY-HYDROGEN ADMINISTRATION ON THE VIABILITY AND PROLIFERATION OF VIRUS INFECTED B-LYMPHOCYTES: IMPLICATIONS FOR THE TREATMENT OF COVID-19 AND POST-VIRAL SYNDROME BACKGROUND: According to recent clinical data, molecular hydrogen (H2) and oxy hydrogen (H2/O2) therapies can successfully remediate the debilitating effects of SARS CoV-2 infection in adults. By acting as an effective anti-inflammatory and antioxidative agent, it is reported that H2 administration can improve viral recovery through abatement of the hyperinflammatory response and reduction of inhalation resistance in patients with mild-moderate disease symptoms. Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2), the causative agent of Coronavirus Infectious Disease 2019 (COVID-19), emerged as a novel pathogen in the closing months of 2019. Recently, it has come to light that up to 30% of adults who contract COVID-19 can develop chronic symptoms, lasting longer than 12 weeks. This phenomenon is not unique to COVID-19 and is noted to occur after infection with Ebola, Epstein-Barr, Influenza and Middle-Eastern Respiratory Syndrome Viruses. However, current treatment strategies are not yet well developed and rely upon repurposing of such medications as antiviral, corticosteroid, immunosuppressant and oxygen therapies, all of which have had limited efficacy in reducing acute COVID-19 symptomology and associated post-viral syndrome. OBJECTIVES: To analyse the effect oxy-hydrogen (H2/O2) may have on virus-infected cells, and the likelihood of reducing the sequalae associated with COVID-19 and post-viral syndrome, the present study examines the effect of H2/O2 administration on Epstein-Barr Virus-infected B-lymphocytes. Grace Russell 1 , AdamThomas 1 , Alexander Nenov 2 , John. T. Hancock 1 1 University of the West of England, Coldharbour Lane, Bristol, UK, 2 Water Fuel Engineering, Unit 3, Church Street, Wakefield, UK, Grace.Russell@uwe.ac.uk

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